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Protein Engineering Biochemistry Scientist (all genders)

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Bayer

3d ago

  • Job
    Full-time
    Mid & Senior Level
  • Science
    Research & Development
  • Wuppertal

AI generated summary

  • You hold a PhD in biochemistry or related field, have hands-on experience with biochemical assays, mammalian cell culture, and protein analysis, and possess strong teamwork and analytical skills.
  • You will design and execute assays, evaluate protein-ligase enzymes, manage projects, coordinate across teams, and share experimental results in a collaborative environment.

Requirements

  • You hold a PhD in biochemistry, cell biology, in vitro pharmacology (all genders) or a related discipline; Postdoctoral research experience is a plus
  • You bring essential hands-on experience with biochemical assays, including ELISA and fluorescence- / UV-based assays (preferably HTS compatible)
  • You have experience in mammalian cell-culture, skills in the cultivation of bacteria and/or yeast are a plus
  • You demonstrate competency in protein analytical methods and enzyme kinetics
  • You demonstrate competencies in rational or semi-rational enzyme design and / or Structural Biology and experience in protein-ligase enzymology, as well as skills in proteomics, mass spectrometry and protein purification are beneficial
  • You exhibit excellent interpersonal and teamwork skills, outstanding analytical thinking, as well as enthusiasm for hands-on bench work
  • You show curiosity and passion for research
  • You are fluent in English, both written and spoken

Responsibilities

  • You play a hands-on bench scientist (all genders) role designing, validating and executing biochemical and cell-based assays
  • You evaluate protein-ligase enzymes and characterize their activity profile in relevant assay formats
  • You scout, evaluate, implement and run state-of-the-art high throughput compatible proximity labeling assays for protein ligases
  • You co-design and manage a Protein Engineering project for engineering the labeling profile of protein-ligase enzymes
  • You perform or support genotype/phenotype correlation of functional enzyme variants and the design of enzyme libraries
  • You coordinate Protein Engineering work packages across various project team functions, including Screening, Molecular Biology and Proteomics
  • You provide and exchange experimental results frequently within local and international project teams

FAQs

What is the job title for this position?

The job title is Protein Engineering Biochemistry Scientist (all genders).

What qualifications are required for this role?

A PhD in biochemistry, cell biology, in vitro pharmacology, or a related discipline is required. Postdoctoral research experience is a plus.

What type of experience is essential for this position?

Essential hands-on experience with biochemical assays, including ELISA and fluorescence- / UV-based assays (preferably HTS compatible) is required.

Is experience in mammalian cell culture necessary?

Yes, experience in mammalian cell culture is necessary, and skills in the cultivation of bacteria and/or yeast are a plus.

Will I be working on protein engineering projects?

Yes, you will co-design and manage a Protein Engineering project focused on engineering the labeling profile of protein-ligase enzymes.

What soft skills are emphasized for this position?

Excellent interpersonal and teamwork skills, outstanding analytical thinking, enthusiasm for hands-on bench work, curiosity, and passion for research are emphasized.

Where is this position located?

The position is located in Wuppertal-Aprath, North Rhine Westphalia, Germany.

What does the benefits package include?

The benefits package includes a competitive compensation package, flexible work arrangements, family support, professional growth opportunities, health awareness measures, and a commitment to diversity and inclusion.

Is fluency in English required for this role?

Yes, fluency in English, both written and spoken, is required.

How does Bayer embrace diversity in the workplace?

Bayer welcomes applications from all individuals, regardless of various personal characteristics, and is committed to creating an inclusive work environment.

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Bayer

Science for a better life

Science & Healthcare
Industry
10,001+
Employees
1863
Founded Year

Mission & Purpose

Bayer is a global enterprise with core competencies in the Life Science fields of health care and agriculture. Our products and services are designed to benefit people and improve their quality of life. At the same time, we aim to create value through innovation, growth and high earning power. Our products help address some of today’s biggest challenges, including global population growth, an aging society and the need to make efficient – and, wherever possible, sustainable – use of natural resources. In line with our mission “Bayer: Science For A Better Life,” we aim to improve people’s quality of life by preventing, alleviating or curing diseases. We also help provide an adequate supply of high-quality food, feed and renewable plant-based raw materials. For these endeavors, we focus on developing and successfully commercializing innovative products and solutions based on scientific knowledge.