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Research Associate- Pellegrini Group (Fixed Term)

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University of Cambridge

2mo ago

  • Job
    Full-time
    Mid Level
  • Science
    Research & Development
  • Cambridge

AI generated summary

  • You must have experience in producing recombinant multi-protein assemblies in insect or mammalian cells, plus knowledge of quantitative biophysical techniques for macromolecular interaction characterization.
  • You will reconstitute and characterize protein complexes for DNA repair using biochemical methods, protein engineering, and advanced biophysical techniques.

Requirements

  • In-depth experience of production of recombinant multi-protein assemblies by expression in insect cells and/or mammalian cells is required.
  • Knowledge of quantitative biophysical techniques for characterisation of macromolecular interactions would be an important advantage.

Responsibilities

  • The successful applicant will work on biochemical reconstitution and structural characterisation of protein complexes important for Homology-Directed DNA Repair and genomic stability.
  • To achieve this goal, the successful candidate will use a multi-disciplinary approach that includes preparative biochemistry of multi-protein complexes, protein engineering and state-of-the-art biophysical and structural techniques.
  • In-depth experience of production of recombinant multi-protein assemblies by expression in insect cells and/or mammalian cells is required.
  • Knowledge of quantitiative biophysical techniques for characterisation of macromolecular interactions would be an important advantage.

FAQs

What is the application deadline for the Research Associate position?

The application deadline is not specified; however, applicants should submit their materials as soon as possible since the funding is available from 01 December 2024.

What are the qualifications needed for this position?

In-depth experience in the production of recombinant multi-protein assemblies by expression in insect cells and/or mammalian cells is required, along with knowledge of quantitative biophysical techniques for characterizing macromolecular interactions being advantageous.

Who should I contact for informal inquiries about the position?

Informal inquiries should be directed to Professor Luca Pellegrini at lp212@cam.ac.uk.

Is this position fixed-term?

Yes, this position is fixed-term, with funding available until 31 May 2026 in the first instance.

What materials should I include in my application?

Applicants should submit a CV with a list of relevant publications, a cover letter explaining their suitability for the position, and contact information for at least two referees.

Is there a focus on diversity and inclusion in the hiring process?

Yes, the University actively supports equality, diversity, and inclusion and encourages applications from all sections of society.

Can you provide the reference number for this job?

Yes, please quote reference PH43820 in your application and any correspondence about this vacancy.

Who should I contact for questions about the application process?

For questions about this vacancy or the application process, please contact personnel@bioc.cam.ac.uk.

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